Folding@Home - Help Unlock the Mysteries of Disease!

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jdl
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Folding@Home - Help Unlock the Mysteries of Disease!

Post by jdl » Sun May 20, 2012 5:24 pm

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There's a program that's been going on ever since October 1, 2000 called Folding@Home (F@H). Basically, it's about the way proteins fold and misfold. Proteins that misfold can lead to health problems and diseases like Alzheimer's, Mad Cow (BSE), CJD, ALS, Huntington's, Parkinson's disease, and many cancers. F@H is here to research the way they misfold, to help develop medicines to prevent misfolding!

How F@H works is:

You download their working client, and get assigned a Work Unit (WU). A WU is just a little bit of the simulation for 1 protein's folding (called projects). Each project is split up into these WUs and once all the WUs for the project is complete, the scientists get the simulation for the folding. The client's core starts simulating the folding in the background of your computer by crunching numbers and all sorts of scientific stuff, and it'll take a few days depending on the size of the WU, or, how many steps it has to simulate. Once all the info is complete for the WU, the client will automatically upload the information that you helped make from your computer to their servers, and the scientists will look at it from there. Afterward, the servers will automatically assign the client another WU. Running F@H takes barely any resources at all, it's mainly using your CPU based on how much of it you want it to use (the more the faster it gets done). You can also use a PS3 to run F@H, and I heard it's EXTREMELY fast at processing WUs, but I don't know since I don't have one.
WUs have a deadline that they must be completed in, otherwise the client will drop the WU and their servers will assign it to someone else to complete while you can try again with a different WU.

I started folding a unit yesterday and then stopped it while I sleep, since I don't like my computer running all night long (except on special occasions where I need to download something big). I've had it running all morning today and it's already at 12% at the time I'm posting this.

Soooo really all this program is, is a "While you're on Youtube or typing a paper up or playing a game, you can be helping the world at the same time!" kind of thing, so why not have it running just because? :D

If you want to download it, you can visit their site here:
http://folding.stanford.edu/
You may have to allow the program though your firewall, and run it as administrator for it to work and upload properly!

Happy Folding.
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Kilicool64
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Post by Kilicool64 » Thu May 24, 2012 1:49 pm

It's always crashing when I try to use it, so my PC can't help. :stinkysad:
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Post by jdl » Thu May 24, 2012 4:18 pm

Kilicool64 wrote:It's always crashing when I try to use it, so my PC can't help. :stinkysad:
Aw, that's too bad. :(
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VirtLands
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Folding@Home

Post by VirtLands » Thu May 24, 2012 6:59 pm

Hi, I heard about this,
Folding@Home is similar in the way it works to Seti@Home,

{ Seti@Home searches for extraterrestrial signal & life. }

My guess is that Folding@home shows an optional graphic representation
of the progress your computer does.

And it may take a bite out of your CPU. {Fortunately I have dual-Core ;)}
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Folding@Home: http://folding.stanford.edu/English/HomePage
Seti@Home: http://setiathome.berkeley.edu/

You may browse the Distributed Computing Stats:
http://stats.free-dc.org/stats.php?page ... 5c1ebb11ce

There's a chart of other distributed projects :

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__________________________________________________

I just tried the Folding@Home software on my laptop,
and it uses 100% (of both cores), causes my computer to be
sluggish. I think my PC is too slow for this.

Yup, my PC is too slow for Folding@Home, it bit the dust...
Last edited by VirtLands on Thu May 24, 2012 7:53 pm, edited 1 time in total.
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VirtLands
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more @Home

Post by VirtLands » Thu May 24, 2012 7:50 pm

Other news:

If your PC is too slow for Folding@Home like mine is, then you can
try these others, (hopefully less taxing projects):

Help find primes, join the PrimeGrid: http://www.primegrid.com/

PrimeGrid's primary goal is to bring the excitement of prime
finding to the "everyday" computer user. By simply downloading and
installing BOINC and attaching to the PrimeGrid project, participants can
choose from a variety of prime forms to search. With a little patience,
you may find a large or even record breaking prime and enter into Chris
Caldwell's The Largest Known Primes Database as a Titan!


Join the Great Internet Mesenne Prime Search:
http://en.wikipedia.org/wiki/Great_Inte ... ime_Search
http://en.wikipedia.org/wiki/Mersenne_prime
http://www.mersenne.org/


help search for spinning neutron stars:
http://en.wikipedia.org/wiki/Einstein@Homea
http://einstein.phys.uwm.edu/

predict the biologically active structure of proteins {POEM@HOME} :
http://stats.free-dc.org/stats.php?page=proj&proj=poe
{ no, it's not about poetry..; you thought it was poetry, but it ISN'T. }

Solve Goldbach's conjecture: { NOT YET AN ACTUAL PROJECT }

http://goldbach.pl/olib/
http://mathworld.wolfram.com/GoldbachConjecture.html
http://en.wikipedia.org/wiki/Goldbach%27s_conjecture
What is the Goldbach's weak conjecture? The Goldbach's weak conjecture
states that every odd number greater than 7 can be expressed as the
sum of three odd primes. Liu Ming-Chit and Wang Tian-Ze proved that for
numbers greater than 2÷101346 Goldbach's weak conjencture is true,
so checking every number under this figre is perfect for using Distributing
Computing architecture like BOINC. And this would make the weak
Goldbach conjecture effectively proved.


Help solve the ABC Conjecture, { ABC@Home }:
http://abcathome.com/
The abc conjecture (also known as Oesterlé–Masser conjecture) is a
conjecture in number theory, first proposed by Joseph Oesterlé and
David Masser in 1985. The conjecture is stated in terms of three positive
integers, a, b and c (whence comes the name), which have no common
factor and satisfy a + b = c. If d denotes the product of the distinct prime
factors of abc, the conjecture essentially states that d is rarely much
smaller than c.


Join MilkyWay@Home:
http://en.wikipedia.org/wiki/Milkyway@home
MilkyWay@home is a volunteer distributed computing project in
astrophysics running on the Berkeley Open Infrastructure for Network
Computing (BOINC) platform. Using spare computing power from over
38,000 computers run by over 27,000 active volunteers as of November
2011,[1] the MilkyWay@home project aims to generate accurate three-
dimensional dynamic models of stellar streams in the immediate vicinity
of our Milky Way galaxy. With SETI@home and Einstein@home, it is the
third computing project of this type that has the investigation of
phenomena in interstellar space as its primary purpose. Its secondary
objective is to develop and optimize algorithms for distributed computing.


Here's a massive list of other distributed computing projects to consider:
http://en.wikipedia.org/wiki/List_of_di ... g_projects
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Post by jdl » Thu May 24, 2012 8:12 pm

I'm not sure how much CPU is used for the newest F@H Client, since I've been using an older version located here:
http://folding.stanford.edu/English/Download2011

I'm using version 6.23 (Systray version).
It says around 50% of the CPU is being used for me (dual core as well) in task manager, but you can still configure it to use even less if necessary.

Right now I'm still working on my 1st WU (74% done, should be done in a couple more days).

I'm going to check these others out, thanks virtlands. :D
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